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Best Enzyme Cleaner For Dogs (2024 Update)

Finding the right enzyme cleaner for your dog can make a world of difference in keeping their space fresh and clean. With so many options on the market, it’s important to consider a few key factors before making a purchase.

First, examine the ingredients. Enzyme cleaners work by using natural enzymes that target the compounds in pet stains and odors to break them down on a molecular level. Look for cleaners that contain protease, amylase and lipase enzymes as well as live bacterial cultures. Stay away from cleaners with heavy fragrances and harsh chemicals.

Next, think about application. Will you need a cleaner that can tackle set-in stains or will a general cleaner for maintenance be enough? Some cleaners come as sprays that can be applied directly to problem areas while others are formulated for use in carpet cleaners and washing machines. Consider your particular cleaning needs.

You’ll also want to factor in safety. Make sure any cleaner you choose is non-toxic and pet safe when dried. The best cleaners will be hypoallergenic and residue-free. Go with a reputable brand known for natural, gentle ingredients.

Choosing the ideal enzyme cleaner involves asking the right questions. What kind of stains will it tackle? How thoroughly will it eliminate odors? Will it be safe to use around pets and children? Once you determine the answers, you’ll find the perfect product for healthy, odor-free cleanliness.

20 Best Enzyme Cleaner For Dogs (20 Sellers)

1. Trinova Natural Pet Stain And Odor Remover Eliminator Advanced Enzyme Cleaner Spray

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2. Angry Orange Enzyme Stain Cleaner & Pet Odor Eliminator, 32oz

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3. Angry Orange Bio-Enzyme Pet Stain And Odor Eliminator (32 Oz) – Fresh Clean

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Is Discontinued By Manufacturer No
Package Dimensions 9.53 x 6.06 x 3.86 inches; 2.29 Pounds
Formulation Type Concentrated
Specific Uses For Product Organic, Fights Odor, Stain Remover, Natural

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4. Rocco & Roxie Professional Strength Pet Stain & Odor Eliminator Enzyme

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Size 32 oz

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5. Nature's Miracle Stain & Odor Remover – 32 Oz

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Weight 2 lb

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6. Nature's Miracle Stain & Odor Remover Foam, Dog, Enzymatic Formula – 17.5 Oz

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7. Natures Miracle Stain & Odor Remover, Dog – 32 Fl Oz

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Units in Package 1
Unit Size 32 fl oz
Directions 1. Apply. 2. Wait: 10 min. 3. Blot. People and pets should not be allowed on treated areas until product has dried. Directions for Use: Before using, test surfaces to be treated for color fastness by applying to a hidden area. Wait 1 hour, then wipe with cloth. If color is removed from the test area, do not use Nature's Miracle Stain & Odor Remover on those surfaces. Do not use on untreated hardwood, leather, suede, silk or wool specialty fabrics. Always use this product full strength. Do not dilute. Always use Nature's Miracle Stain & Odor Remover products first. Other cleaners and detergents may fail and chemically set stains that will be impossible to remove. For Stain Removal: 1. Wipe up as much of the stain as possible, then thoroughly soak stain with this product 2. Allow to work for 10 minutes, then blot up stain with a clean cloth. 3. Allow area to dry for 24 hours. 4. For severe, old or stubborn stains on carpeting or fabrics (feces or vomit/hairball), follow steps 1-2 above and follow with gently scrubbing the stain with a soft bristle brush for 1 minute, then allow to dry for 24 hours. For Odor Elimination: 1. Wipe up excess odor-causing material, then thoroughly soak area with this product. Saturation is important so that this product can penetrate deeply to the odor source. In carpeting, this may mean lifting carpet and applying directly to the pad and floor 2. Do not wipe up excess. 3. Leave treated area wet and let it air dry. Odor will fade as this product dries. Complete odor elimination only happens when all odor sources are reached 4. For severe, old or stubborn odors on carpeting or fabrics, saturate a towel with water and lay over the treated area, letting sit for 1 to 2 hours. This will allow the bacterial enzymatic activity to break down and consume more of the odor. Usage Guidelines: Spot Treatment Soft Surfaces: Stain Size [Diameter in Inches]: 1-2 inch; Recommended Usage [Ounces]: 1/2 ounce. Stain Size [Diameter in Inches]: 3-6 inch; Recommended Usage [Ounces]: 1 ounce. Stain Size [Diameter in Inches]: 6-9 inch; Recommended Usage [Ounces]: 2 ounces Stain Size [Diameter in Inches]: 9-12 inch; Recommended Usage [Ounces]: 4 ounces. Spot Treatment Hard Surfaces: Stain Size [Diameter in Inches]: 1-2 inch; Recommended Usage [Ounces]: 1/4 ounce. Stain Size [Diameter in Inches]: 3-6 inch; Recommended Usage [Ounces]: 1/2 ounce. Stain Size [Diameter in Inches]: 6-9 inch; Recommended Usage [Ounces]: 1 ounce. Stain Size [Diameter in Inches]: 9-12 inch; Recommended Usage [Ounces]: 2 ounces. Larger Area Stain Treatment Soft Surfaces: Stain Size [Square Feet]: 1 x 1 ft; Recommended Usage [Ounces]: 4 ounces. Stain Size [Square Feet]: 2 x 2 ft; Recommended Usage [Ounces]: 8 ounces. Stain Size [Square Feet]: 3 x 3 ft; Recommended Usage [Ounces]: 32 ounces. Larger Area Stain Treatment Hard Surfaces: Stain Size [Square Feet]: 1 x 1 ft; Recommended Usage [Ounces]: 2 ounces. Stain Size [Square Feet]: 2 x 2 ft; Recommended Usage [Ounces]: 4 ounces. Stain Size [Square Feet]: 3 x 3 ft; Recommended Usage [Ounces]: 16 ounces. Storage and Disposal: Storage: Store container upright and tightly sealed in a dry place out of reach of children and pets. Keep from freezing or overheating. Disposal: Place in trash or offer for recycling if available.
Ingredients Water, Isopropyl Alcohol, Surfactants, Citrus Fragrance, Preservative, Enzymatic Blend, Odor Counteractant.
Warnings Keep out of reach of children and pets. No adverse effects are expected, but if ingestion or irritation occurs, consult a medical professional.

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8. Simple Solution Pet Stain & Odor Remover With Pro-Bacteria And Enzyme Formula, 1-Gallon

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9. Natures Miracle Stain & Odor Remover, Dog, Foam – 17.5 Oz

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Units in Package 1
Unit Size 17.5 oz
Directions 1. Apply. 2. Wait: 10 min. 3. Blot. People and pets should not be allowed on treated areas until product has dried. Directions for Use: Before using, test surfaces to be treated for color fastness by applying to a hidden area. Wait 1 hour, then wipe with cloth. If color is removed from the test area, do not use Nature's Miracle Stain & Odor Remover Foam on those surfaces. Do not use on untreated hardwood, leather, suede, silk or wool specialty fabrics. Always use this product full strength. Do not dilute. Always use Nature's Miracle Stain & Odor Remover products first. Other cleaners and detergents may fail and chemically set stains that will be impossible to remove. For Stain Removal: 1) Wipe up as much of the stain as possible. 2) Shake can well. 3) Hold can upside down and point toward treatment area. Spray until foam is covering the mess. Foam will break down into carpet. penetrating the mess. 4) Allow to work for 10 minutes then blot up stain with a clean cloth. 5) Allow area to dry for 24 hours. 6) For severe, old or stubborn stains (feces or vomit/hairball), follow steps 1-4 above and follow with gently scrubbing the stain with a soft bristle brush for 1 minute, then allow to dry for 24 hours. For Odor Elimination: 1) Wipe up excess odor-causing material. 2) Shake can well. 3) Hold can upside down and point toward treatment area. Spray area with product until foam is covering the area. Saturation is important so that this product can penetrate deeply to the odor source. 4) Do not wipe up excess. 5) Leave treated area wet and let it air dry. Odor will fade as this product dries. Complete odor elimination only happens when all odor sources are reached. Storage and Disposal: Contents under pressure. Keep away from heat, sparks and open flame Exposure to temperatures above 120 degrees F may cause bursting. Storage: Store in a cool, dry place away from children. Disposal: Do not puncture or incinerate! Place in trash or offer for recycling if available.
Warnings Caution: Contents under pressure. Precautionary Statements: Keep out of reach of children and pets caution. contents under pressure. Container may explode if heated. Do not expose to heat or store at temperatures above 120 degrees F. Do not puncture or incinerate container. Use with adequate ventilation. First Aid: First Aid Treatment: If Swallowed: Call a Poison Control Center or doctor immediately. Do not induce vomiting. If in Eyes: Rinse with water for 15 minutes. If on skin: Rinse well with water. If Breathed in: Move person into fresh air.

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10. Nature's Miracle 1 Gal Dog Urine Destroyer

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Hazardous Material No
Brand Natures Miracle
Width 5.10
Length 7.63
Height 12.25

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11. Furryfreshness Premium Pet Stain & Smell Remover – Permanently Evaporates Stains

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Weight 2.1 lb

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12. Bissell Professional Stain & Odor – 22 Fl Oz

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Units in Package 1
Unit Size 22 fl oz
Directions Before You Clean: Test a small, hidden area for colorfastness. Wait until dry. If color is affected, do not use. For upholstery, use on manufacturer's code WS or W only. How To Use: 1. Shake well, turn nozzle to spray position and generously spray evenly over soled area. 2. For Spot Cleaning and Heavily Soiled Areas: Thoroughly saturate soiled area and cover with a clean, damp cloth so area remains moist for up to 12 hours. Uncover area to dry. 3. Prior to Machine Deep Cleaning: After spraying, let sit for 3-5 minutes, deep clean following machine's user guide. Follow up with step 2 for heavily soiled areas. For best results: Do not use with other household cleaners as they may deactivate the enzyme cleaning action. Immediately clean spot and stains when they occur. Remove excess liquid or solid particles from stain before cleaning. For best results, when deep cleaning, use deep cleaning machine formula.
Warnings Eye irritant. Contains nonionic surfactants. In case of eye contact, flush thoroughly with water for at least 15 minutes. If irritation persists, consult physician. Keep out reach of children.

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13. Biokleen Bac-Out Stain & Odor Remover – 32 Oz

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Units in Package 1
Unit Size 32 oz
Directions Directions for Use: To remove stains + odors , remove excess waste, saturate affected area, let sit for 5 minutes or more. Blot with rag. Repeat process if needed. Does not need to be rinsed. Try Bac-Out on pet accidents, carpet, wine, diapers and pails, laundry, disposals, garbage cans and more.
Ingredients Water (Filtered), Glycerin (Vegetable), Caprylyl/Capryl Glucoside (Plant Based Surfactant), C10-16 Alkyl Glucoside (Plant Based), Laureth 7 (Plant Based Surfactant), Citrus Terpenes, Dipropylene Glycol, Benzisothiazolinone, Viable Bacillus Cultures.
Warnings Keep out of reach of children. Caution: In case of eye contact, flush with cool water for 15 minutes. In case of ingestion, do not induce vomiting; drink plenty of water to dilute.

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14. Nature's Miracle Advanced Formula Stain And Odor Remover – 1 Gal Jug

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Is Discontinued By Manufacturer No
Product Dimensions 5.6 x 5.6 x 7.8 inches; 8.02 Pounds
Item Package Dimensions L x W x H 11.93 x 6.61 x 6.34 inches
Item Dimensions LxWxH 5.6 x 5.6 x 7.8 inches

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15. Nature's Miracle Orange-Oxy Stain & Odor Remover 24oz

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16. Woolite Pet Stain & Odor Remover + Oxy, Fresh Blossom Scent – 22 Fl Oz

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Units in Package 1
Unit Size 22 fl oz
Directions Before Cleaning: Remove solid residue and blot excess liquid with a clean, colorfast, absorbent cloth. Test for colorfastness on a hidden area. If color is affected, do not use this product. Before using this product on upholstery, look for manufacturer's cleanability code tag. Use on upholstery coded WS or W. Do not use on upholstery coded X or S. Do not use on velvet, silk, vinyl or leather upholstery. How to Use: Spray soiled area and let stand for 5 minutes to penetrate stain. Do not saturate. Gently blot or rub area with a clean, damp colorfast cloth. Rinse and repeat as needed. Stay off and keep kids & pets off cleaned area until dry and vacuumed. For Best Results: Treat stains immediately. Stains allowed to dry and set can cause bleaching and may be difficult to remove. To more effectively clean stains such as pet urine, a larger area around the stain should be treated and cleaned. Do not expose to heat or store at temperatures above 120 degrees F.
Warnings Caution: Avoid eye contact. In case of eye contact, flush thoroughly with water for at least 15 minutes. Get medical attention if irritation develops or persist. Keep out of reach of children & pets.

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17. Nature's Miracle – Advanced Stain & Odor Remover, 32 Oz

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18. Natures Miracle Stain & Odor Remover, Dual Action, Oxy Formula – 128 Fl Oz

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Units in Package 1
Unit Size 128 fl oz
Directions 1)Before using, test surfaces to be treated for color fastness by applying to a hidden area; wait five minutes then wipe with cloth. If color is removed from the test area, do not use Nature's Miracle Oxy Formula on those surfaces. 2) Always use Nature's Miracle Oxy Formula full strength. 3)Always use Nature's Miracle Oxy Formula first! Other cleaners and detergents may fail and chemically set stains that will be impossible to remove. 4) Shake well before using. For Stain Removal: 1)Wipe up as much of stain as possible, then thoroughly soak stain with Nature's Miracle Oxy formula. 2) Wait five minutes, then wipe away stain with a cloth. 3) While treated areas dry, keep pets away. For tough stains, use a stiff bristle brush. If stain is not completely removed, re-soak area and allow Nature's Miracle Oxy Formula to work for one hour, then wipe stain with a cloth. For Odor Elimination: 1) Wipe up excess odor-causing material, then thoroughly soak area with Nature's Miracle Oxy Formula. 2)Wait five minutes, then blot dry with a cloth. Allow to dry completely before expecting complete odor elimination. 3) While treated areas dry, keep pets away. For tough odors in carpets (eg urine) apply enough to reach all odor-causing material. This may mean lifting carpet and applying directly to the pad and floor. Wait one hour, then blot dry. Allow treated area to air dry completely before expecting complete odor elimination. For Laundry Use: Saturate stain and odor areas with Nature's Miracle Oxy Formula at full strength before washing. Then, wash as usual.
Ingredients Water, Oxygen Concentrate, Orange Extract, Fragrance.
Warnings Keep closed when not in use. Keep out of reach of children. Do not apply directly on pets. Store at room temperature.

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19. Nature's Miracle Organic Oxy Cat Stain & Odor Remover

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20. Petzyme Pet Stain Remover & Odor Eliminator, Enzyme Cleaner For Dogs, Cats Urine, Feces And More, 32 Fl Oz Spray

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spray it on, smell is gonebubba2013000
Amazing my house now smells lovely again. Better than any disinfectantnelliedeen

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